Assistive Communication
For people with locked-in syndrome – the inability to move and to speak despite being fully awake and alert (for example, due to brainstem injury or ALS) – restoration of easy communication is a priority. Our research team is developing technologies that would re-enable the ability to control a cursor on a computer screen or to type on a virtual keyboard, simply by thinking about the movement of one’s own hand (for example, as if controlling a computer mouse).
Related Publications
Jude JJ, Haro S, Levi-Aharoni H, Hashimoto H, Acosta AJ, Card NS, Wairagkar M, Brandman DM, Stavisky SD, Williams ZM, Cash SS, Simeral JD, Hochberg LR, Rubin DB.
Decoding intended speech with an intracortical brain-computer interface in a person with longstanding anarthria and locked-in syndrome
[Preprint]. bioRxiv. 2025 Aug 12: [24 p.]. doi: 10.1101/2025.08.12.668516
Jude JJ, Levi-Aharoni H, Acosta AJ, Allcroft SB, Nicolas C, Lacayo BE, Card NS, Wairagkar M, Brandman DM, Stavisky SD, Willett FR, Williams ZM, Simeral JD, Hochberg LR, Rubin DB
An intuitive, bimanual, high-throughput QWERTY touch typing neuroprosthesis for people with tetraplegia
[In Press, Nature Neuroscience]. medRxiv. 2025 Apr 01: [18 p.]. doi: 10.1101/2025.04.01.25324990
Willett FR, Avansino DT, Hochberg LR, Henderson JM, Shenoy KV.
High-performance brain-to-text communication via handwriting
Nature. 2021 May 12; 593: 249–54. doi: 10.1038/s41586-021-03506-2. Prior version as submitted to bioRxiv.







