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Replay of learned neural firing sequences during rest in human motor cortex.
Cell Reports. 2020 May 5;31:107581.
Willett FR*, Deo DR*, Avansino DT, Rezaii Paymon, Hochberg LR, Henderson JM**, Shenoy KV**
Hand knob area of motor cortex in people with tetraplegia represents the whole body in a compositional way.
Cell. 2020 Mar 26;181:1–14.
Stavisky SD, Willett FR, Wilson GH, Murphy BA, Rezaii P, Avansino DT, Memberg WD, Miller JP, Kirsch RF, Hochberg LR, Ajiboye AB, Druckmann S, Shenoy KV, Henderson JM.
Neural ensemble dynamics in dorsal motor cortex during speech in people with paralysis.
eLife. 2019 Dec 10;8:e46015.
Milekovic T, Bacher D, Sarma AA, Simeral JD, Saab J, Pandarinath C, Yvert B, Sorice BL, Blabe C, Oakley EM, Tringale KR, Eskandar E, Cash SS, Shenoy KV*, Jaimie M. Henderson*, Hochberg LR, Donoghue JP
Volitional control of single-electrode high gamma local field potentials by people with paralysis.
Journal of Neurophysiology. 2019 Apr 11; 121(4): 1428-1450.
Hosman T, Vilela M, Milstein D, Kelemen JN, Brandman DM, Hochberg LR, Simeral JD.
BCI decoder performance comparison of an LSTM recurrent neural network and a Kalman filter in retrospective simulation.
2019 9th International IEEE/EMBS Conference on Neural Engineering (NER), San Francisco, CA, USA. 2019 Mar. pp. 1066-1071.
Nuyujukian P, Albites Sanabria J, Saab J, Pandarinath C, Jarosiewicz B, Blabe CH, Franco B, Mernoff ST, Eskandar EN, Simeral JD, Hochberg LR, Shenoy KV, Henderson JM.
Cortical control of a tablet computer by people with paralysis
PLoS ONE. 2018 Nov 21; 13(11).
Vargas-Irwin CE, Feldman JM, King B, Simeral JD, Sorice BL, Oakley EM, Cash SS, Eskandar EN, Friehs GM, Hochberg LR, Donoghue JP.
Watch, Imagine, Attempt: Motor Cortex Single-Unit Activity Reveals Context-Dependent Movement Encoding in Humans With Tetraplegia
Front Hum Neurosci. 2018 Nov 15;12. doi.org/10.3389/fnhum.2018.00450
Brandman DM, Burkhart MC, Kelemen J, Franco B, Harrison MT, Hochberg LR.
Robust Closed-Loop Control of a Cursor in a Person with Tetraplegia using Gaussian Process Regression.
Neural Computation. 2018 Nov;30(11):2986-3008
Pandarinath C, O'Shea DJ, Collins J, Jozefowicz R, Stavisky SD, Kao JC, Trautmann EM, Kaufman MT, Ryu SI, Hochberg LR, Henderson JM, Shenoy KV, Abbott LF, Sussillo D.
Inferring single-trial neural population dynamics using sequential auto-encoders.
Nature Methods. 2018.
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Signal processing methods for reducing artifacts in microelectrode brain recordings caused by functional electrical stimulation.
J Neural Eng. 2018 Apr;15(2)
Milekovic T*, Sarma AA*, Bacher D, Simeral JD, Saab J, Pandarinath C, Sorice BL, Blabe C, Oakley EM, Tringale KR, Eskandar E, Cash SS, Henderson JM, Shenoy KV, Donoghue JP, Hochberg LR.
Stable long-term BCI-enabled communication in ALS and locked-in syndrome using LFP signals.
J. Neurophysiol. 2018 Apr 25;120(1).
Brandman DM, Hosman T, Saab J, Burkhart M, Shanahan B, Ciancibello J, Sarma AA, Milstein DJ, Vargas-Irwin C, Franco B, Kelemen JN, Blabe CH, Murphy BA, Young DR, Willett FR, Pandarinath C, Stavisky SD, Kirsch RF, Walter BL, Ajiboye AB, Cash SS, Eskandar EN, Miller JP, Sweet JA, Shenoy KV, Henderson JM, Jarosiewicz B, Harrison MT, Simeral JD, Hochberg LR
Rapid calibration of an intracortical brain computer interface for people with tetraplegia.
J. Neural Eng. 2018 Jan 24.
Willett FR, Murphy BA, Young DR, Memberg WD, Blabe CH, Pandarinath C, Franco B, Saab J, Walter BL, Sweet JA, Miller JP, Henderson JM, Shenoy KV, Simeral JD, Jarosiewicz B, Hochberg LR, Kirsch RF, Ajiboye AB.
A comparison of intention estimation methods for decoder calibration in intracortical brain-computer interfaces.
IEEE Eng Med Biol Soc. 2017 Dec 14. doi: 10.1109/TBME.2017.2783358
Milstein DJ, Pacheco JL, Hochberg LR, Simeral JD, Jarosiewicz B, Sudderth EB
Multiscale semi-Markov dynamics for intracortical brain-computer interfaces.
31st Conference on Neural Information Processing Systems (NIPS). 2017 Dec.
Young D, Willett F, Memberg WD, Murphy B, Walter B, Sweet JA, Miller J, Hochberg L, Kirsch RF, Ajiboye AB.
Signal processing methods for reducing artifacts in microelectrode brain recordings caused by functional electrical stimulation.
J. Neural Eng. 2017 Dec 4. doi: 10.1088/1741-2552/aa9ee8. [Epub ahead of print]
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Retrospectively supervised click decoder calibration for self-calibrating point-and-click brain-computer interfaces.
J Physiol Paris. 2017 Mar 8. pii: S0928-4257(17)30010-4. doi: 10.1016/j.jphysparis.2017.03.001. [Epub ahead of print]
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IEEE Trans Neural Syst Rehabil Eng. 2017 Mar 2. doi: 10.1109/TNSRE.2017.2677443. [Epub ahead of print]
Ajiboye AB, Willett FR, Young DR, Memberg WD, Murphy BA, Miller JP, Walter BL, Sweet JA, Hoyen HA, Keith MW, Peckham PH, Simeral JD, Donoghue JP, Hochberg LR, Kirsch RF
Restoration of reaching and grasping movements through brain-controlled muscle stimulation in a person with tetraplegia: a proof-of-concept demonstration
The Lancet. 2017 Mar 28.
Pandarinath C, Nuyujukian P, Blabe CH, Sorice BL, Saab J, Willett FR, Hochberg LR, Shenoy KV, Henderson JM.
High performance communication by people with paralysis using an intracortical brain-computer interface.
eLife 2017;6:e18554.
Willett FR, Murphy BA, Memberg WD, Blabe CH, Pandarinath C, Walter BL, Sweet JA, Miller JP, Henderson JM, Shenoy KV, Hochberg LR, Kirsch RF, Ajiboye AB.
Signal-independent noise in intracortical brain-computer interfaces causes movement time properties inconsistent with Fitts’ law.
J Neural Eng. 2017 Feb 8;14(2):026010. doi: 10.1088/1741-2552/aa5990. [Epub ahead of print]
Willett FR, Pandarinath C, Jarosiewicz B, Murphy BA, Memberg WD, Blabe CH, Saab J, Walter BL, Sweet JA, Miller JP, Henderson JM, Shenoy KV, Simeral JD, Hochberg LR, Kirsch RF, Ajiboye AB.
Feedback control policies employed by people using intracortical brain-computer interfaces.
J Neural Eng. 2016 Nov 30;14(1):016001. [Epub ahead of print]
Jarosiewicz B, Sarma AA, Bacher D, Masse NY, Simeral JD, Sorice B, Oakley EM, Blabe C, Pandarinath C, Gilja V, Cash SS, Eskandar EN, Friehs G, Henderson JM, Shenoy KV, Donoghue JP, Hochberg LR
Virtual typing by people with tetraplegia using a self-calibrating intracortical brain-computer interface
Sci Transl Med. 2015 Nov 11;7(313):313ra179. doi: 10.1126/scitranslmed.aac7328.
Gilja V*, Pandarinath C*, Blabe CH, Nuyujukian P, Simeral JD, Sarma AA, Sorice BL, Perge JA, Jarosiewicz B, Hochberg LR, Shenoy KV, Henderson JM.
Clinical translation of a high-performance neural prosthesis.
Nat Med. 2015 Oct;21(10):1142-5. doi: 10.1038/nm.3953. Epub 2015 Sep 28.
Pandarinath C, Gilja V, Blabe CH, Nuyujukian P, Sarma AA, Sorice BL, Eskandar EN, Hochberg LR, Henderson JM, Shenoy KV
Neural population dynamics in human motor cortex during movements in people with ALS.
eLife. 2015; 4: e07436.
Bacher D, Jarosiewicz B, Masse NY, Stavisky SD, Simeral JD, Newell K, Oakley EM, Cash SS, Friehs G, Hochberg LR
Neural Point-and-Click Communication by a Person With Incomplete Locked-In Syndrome.
Neurorehabil Neural Repair. 2015 Jun;29(5):462-71. doi: 10.1177/1545968314554624. Epub 2014 Nov 10.
Malik WQ, Hochberg LR, Donoghue JP, Brown EN
Modulation depth estimation and variable selection in state-space models for neural interfaces.
IEEE Trans Biomed Eng. 2015 Feb;62(2):570-81. Epub 2014 Sep 26.
Yin M, Borton DA, Komar J, Agha N, Lu Y, Li H, Laurens J, Lang Y, Li Q, Bull C, Larson L, Rosler D, Bezard E, Courtine G, Nurmikko AV.
Wireless neurosensor for full-spectrum electrophysiology recordings during free behavior.
Neuron. 2014 Dec 17;84(6):1170-82. doi: 10.1016/j.neuron.2014.11.010. Epub 2014 Dec 4.
Masse NY, Jarosiewicz B, Simeral JD, Bacher D, Stavisky SD, Cash SS, Oakley EM, Berhanu E, Eskandar E, Friehs G, Hochberg LR, Donoghue JP
Non-causal spike filtering improves decoding of movement intention for intracortical BCIs.
J Neurosci Methods. 2014 Oct 30;236:58-67. Epub 2014 Aug 13.
Perge JA, Zhang S, Malik WQ, Homer ML, Cash S, Friehs G, Eskandar EN, Donoghue JP, Hochberg LR
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J Neural Eng. 2014 Aug;11(4):046007. Epub 2014 Jun 12.
Truccolo W, Ahmed OJ, Harrison MT, Eskandar EN, Cosgrove GR, Madsen JR, Blum AS, Potter NS, Hochberg LR, Cash SS
Neuronal ensemble synchrony during human focal seizures.
J Neurosci. 2014 Jul 23;34(30):9927-44.
Park YS, Hochberg LR, Eskandar EN, Cash SS, Truccolo W.
Early detection of human focal seizures based on cortical multiunit activity.
Proc IEEE Eng Med Biol Soc. 2014; 2014:5796-9.
Jarosiewicz B, Masse NY, Bacher D, Cash SS, Eskandar E, Friehs G, Donoghue JP, and Hochberg LR
Advantages of closed-loop calibration in intracortical brain-computer interfaces for people with tetraplegia.
J Neural Eng. 2013 Aug;10(4):046012. Epub 2013 Jul 10.
Perge JA, Homer ML, Malik WQ, Cash S, Eskandar E, Friehs G, Donoghue JP, and Hochberg LR
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J Neural Eng. 2013 Jun;10(3):036004. Epub 2013 Apr 10.
Shaikhouni A, Donoghue JP, and Hochberg LR
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J Neurophysiol. 2013 Apr;109(8):2192-204. Epub 2013 Jan 23.
Borton DA, Yin M, Aceros J, Nurmikko A.
An implantable wireless neural interface for recording cortical circuit dynamics in moving primates.
J Neural Eng. 2013 Apr;10(2):026010. doi: 10.1088/1741-2560/10/2/026010. Epub 2013 Feb 21.
Yin M, Borton DA, Aceros J, Patterson WR, Nurmikko AV.
A 100-channel hermetically sealed implantable device for chronic wireless neurosensing applications.
IEEE Trans Biomed Circuits Syst. 2013 Apr;7(2):115-28.
Homer ML, Nurmikko AV, Donoghue JP, and Hochberg LR
Sensors and decoding for intracortical brain computer interfaces.
Annu Rev Biomed Eng. 2013;15:383-405.
Ajiboye AB, Simeral JD, Donoghue JP, Hochberg LR, and Kirsch RF
Prediction of imagined single-joint movements in a person with high-level tetraplegia.
IEEE Trans Biomed Eng. 2012 Oct;59(10):2755-65. Epub 2012 Jul 23.
Hochberg LR, Bacher D, Jarosiewicz B, Masse NY, Simeral JD, Vogel J, Haddadin S, Liu J, van der Smagt P, Donoghue JP
Reach and grasp by people with tetraplegia using a neurally controlled robotic arm.
Nature. 2012 May 17; 485 (7398): 372-5.
Truccolo W, Donoghue JA, Hochberg LR, Eskandar EN, Madsen JR, Anderson WS, Brown EN, Halgren E, and Cash SS
Single-neuron dynamics in human focal epilepsy
Nature Neuroscience. 2011 May;14(5):635-41. Epub 2011 Mar 27. • Editorial: The ups and downs of seizure activity
Kim SP, Simeral JD, Hochberg LR, Donoghue JP, Friehs GM, and Black MJ
Point-and-click cursor control with an intracortical neural interface system by humans with tetraplegia.
IEEE Trans Neural Sys Rehabil Eng. 2011, Apr; 19(2): 193-203.
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Efficient Decoding With Steady-State Kalman Filter in Neural Interface Systems
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Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortex
Brain 2010 Apr 17 133: 1668-1681
Nurmikko AV, Donoghue JP, Hochberg LR, Patterson WR, Song YK, Bull CW, Borton DA, Laiwalla F, Park S, Ming Y, and Aceros J (2010 Feb 25)
Listening to Brain Microcircuits for Interfacing With External World—Progress in Wireless Implantable Microelectronic Neuroengineering Devices.
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Stochastic models for multivariate neural point processes: collective dynamics and neural decoding.
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Truccolo W, Hochberg LR, and Donoghue JP
Collective dynamics in human and monkey sensorimotor cortex: Predicting single neuron spikes.
Nature Neuroscience 2009 Dec 6 (Epub ahead of print)
Song YK, Borton DA, Park S, Patterson WR, Bull CW, Laiwalla F, Mislow J, Simeral JD, Donoghue JP, and Nurmikko AV
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IEEE Trans Neural Syst Rehabil Eng. 2009 Aug;17(4):339-45. Epub 2009 Jun 5.
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Multi-state decoding of point-and-click control signals from motor cortical activity in a human with tetraplegia
3rd International IEEE-EMBS Conference 2007 May:486-489
Hochberg LR and Taylor DM
Intuitive prosthetic limb control.
Lancet. 2007 Feb 3; 369 (9559): 345-6
Song YK, Patterson WR, Bull CW, Borton DA, Li Y, Nurmikko AV, Simeral JD, and Donoghue JP
A brain implantable microsystem with hybrid RF/IR telemetry for advanced neuroengineering applications.
Conf Proc IEEE Eng. Med Biol. Soc. 2007: 445-8
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Neuromotor prosthesis development.
Med Health R I. 2007 Jan ; 90 (1): 12-5
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Nature. 2006 Jul 13; 442 (7099): 164-71
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BCI Meeting 2005–workshop on clinical issues and applications.
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Proceedings of the 26th Annual International Conference of the IEEE EMBS, San Francisco, CA. 2004.
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