BrainGate Publication Timelines AllSelected Achievements Neuroscience Neural EngineeringCommunicationMovement RestorationSpeech RestorationNeurotherapeutics Co-occurring ripple oscillations facilitate neuronal interactions between cortical locations in humans. Read the paper Jan 1995 Intracortical recording of brain activity for control of limb prostheses Read the paper Jan 1997 Cortical control of a robot using a time-delay neural network Read the paper Mar 2002 Instant neural control of a movement signal Read the paper Mar 2003 Robustness of neuroprosthetic decoding algorithms Read the paper 2004 BrainGate clinical trial starts (NCT00912041) at participants’ homes Read the paper Feb 2005 A point process framework for relating neural spiking activity to spiking history, neural ensemble and extrinsic covariate effects Read the paper Mar 2005 Reconstruction of hand movement trajectories from a dynamic ensemble of spiking motor cortical neurons Read the paper Jun 2006 An international discussion on the state of the brain-computer interface field Read the paper Jul 2006 iBCI control of computer cursor, TV, prosthetic hand, simple robotic arm; participants with SCI Read the paper Oct 2006 Prosthesis development for the restoration of limb function Read the paper Oct 2006 Sensors for brain-computer interfaces Read the paper Jan 2007 Neuromotor prosthesis development Read the paper Mar 2007 Nonparametric modeling of neural point processes via stochastic gradient boosting regression Read the paper Mar 2007 Assistive technology and robotic control using motor cortex ensemble-based neural interface systems in humans with tetraplegia Read the paper Apr 2007 Intuitive prosthetic limb control Read the paper May 2007 Multi-state decoding of point-and-click control signals from motor cortical activity in a human with tetraplegia Read the paper Oct 2007 Hybrid RF/IR Telemetry for brain implantable neuroengineering applications Read the paper Sep 2008 Turning thought into action Read the paper Nov 2008 Future applications of neural interface systems Read the paper Dec 2008 Cursor control; participants with brainstem stroke, ALS Read the paper Dec 2008 Neural activity in primary motor cortex correlates with intended movement kinematics in humans with tertraplegia Read the paper Jun 2009 Wireless implantable microelectronic device for transmitting cortical signals transcutaneously Read the paper Jul 2009 The science of neural interface systems Read the paper Dec 2009 Predicting single neuron spikes Read the paper Jan 2010 Stochastic point process framework for the modeling, analysis and decoding of neuronal ensembles Read the paper Feb 2010 Progress in wireless implantable microelectronic neuroengineering devices Read the paper Apr 2010 Decoding 3-D reach and grasp kinematics from high-frequency LFPs in primate primary motor cortex Read the paper Apr 2010 Intracortical microelectrode signals reveal heterogeneous neuronal firing patterns during interictal epileptiform discharges Read the paper Nov 2010 Efficient decoding with steady-state Kalman filter Read the paper Jan 2011 Decoding point-and-click control signals from motor cortical activity in a human with tetraplegia Read the paper Mar 2011 1000+ days of neural cursor control Read the paper Mar 2011 Single-neuron dynamics in human focal epilepsy Read the paper May 2012 Multi-dimensional robotic and prosthetic arm control, coffee drinking Read the paper Jul 2012 Prediction of imagined single-joint movements in a person with high-level tetraplegia Read the paper Feb 2013 Evaluation of implantable wireless neural interface in nonhuman primates Read the paper Apr 2013 Role of intra-day signal instabilities on decoding performance Read the paper Apr 2013 Somatosensory responses in a human motor cortex Read the paper Apr 2013 A 100-channel fully implantable wireless broadband neural recording system Read the paper Jul 2013 Advances in iBCI sensors and decoding Read the paper Jul 2013 Improved iBCI control with closed-loop calibration Read the paper Jun 2014 Field potentials provide comparable offline decoding performance to unsorted spikes Read the paper Jul 2014 Neuronal ensemble synchrony during human focal seizures Read the paper Aug 2014 Early detection of human focal seizures based on cortical multiunit activity Read the paper Sep 2014 Modulation depth estimation and variable selection in state-space models for neural interfaces Read the paper Oct 2014 Speech-specific tuning of neurons in human superior temporal gyrus Read the paper Oct 2014 Non-causally filtering intracortical neural signals improves BCI decoding Read the paper Dec 2014 Wireless use in nonhuman primates Read the paper Apr 2015 The emergence of single neurons in clinical neurology Read the paper Jun 2015 Point-and-click typing at 1,994 days Read the paper Jun 2015 Neural population dynamics in human motor cortex during movements in people with ALS Read the paper Oct 2015 Improved cursor control and speed with ReFIT decoder Read the paper Nov 2015 QWERTY and radial keyboard use, up to 24 correct characters per minute Read the paper Nov 2015 Microdynamics of focal seizure propagation Read the paper Aug 2016 Predicting seizures with intracortical LFPs Read the paper Nov 2016 Feedback control policies employed during active iBCI control Read the paper Jan 2017 Multiscale semi-Markov dynamics for intracortical brain-computer interfaces Read the paper Feb 2017 Typing at 39 correct characters per minute (3.7 bits per second) Read the paper Mar 2017 Review on advances in intracortical BCI technology Read the paper Mar 2017 Recalibration of click decoder using data acquired during practical BCI use Read the paper Mar 2017 iBCI + FES restoration of arm and hand movement Read the paper Dec 2017 Comparing methods for intention estimation for decoder calibration in iBCIs Read the paper Jan 2018 Decoder calibration and cursor control in < 4 minutes Read the paper Jan 2018 Methods for reducing artifacts in iBCI recordings caused by FES stimulation Read the paper Feb 2018 How iBCI movements currently differ from able-bodied movements Read the paper Jul 2018 LFP-based BCI for everyday communication Read the paper Sep 2018 Deep learning via LFADS reveals neural dynamics from single trials Read the paper Nov 2018 A new neural decoder based on gaussian process regression is more resistant to nonstationarities Read the paper Nov 2018 Watching, imagining, or attempting a movement produces a unique pattern of neural activity Read the paper Nov 2018 Control of tablet computer with iBCI Read the paper Mar 2019 Comparison of LSTM vs Kalman decoders Read the paper Apr 2019 Volitional LFP control by poeple with tetraplegia Read the paper Jul 2019 Intracortical neural activity predicts onset of focal seizures Read the paper Dec 2019 Phoneme decoding from hand motor cortex Read the paper Jan 2020 Neural representation of observed, imagined, and attempted force production Read the paper Feb 2020 Speech-related dorsal motor cortex activity does not interfere with iBCI cursor control Read the paper Mar 2020 Improving the BCI user experience with robotic effectors Read the paper Mar 2020 Intracortical microelectrode array signals allow early detection of human epileptic seizures Read the paper Apr 2020 The ‘hand knob’ area of premotor cortex is tuned to the entire body Read the paper May 2020 The Discriminative Kalman Filter for Bayesian Filtering with Nonlinear and Nongaussian Observation Models Read the paper May 2020 Researchers demonstrate replay of learned sequences during rest in human motor cortex Read the paper Aug 2020 Power saving for wireless iBCIs Read the paper Nov 2020 Decoding speech from the ‘hand knob’ area of precentral gyrus Read the paper Jan 2021 The role of middle frontal gyrus in planning movements in response to auditory stimuli Read the paper Jan 2021 Decoding force information across different grasp types Read the paper Mar 2021 Full bandwidth, external wireless home use Read the paper Apr 2021 Proprioceptive feedback via mechanical haptic stimulation increases cursor control performance Read the paper May 2021 Brain-to-text decoding of handwriting Read the paper Jun 2022 Learned Motor Patterns Are Replayed in Human Motor Cortex during Sleep Read the paper Jan 2023 Interim Safety Profile from the Feasibility Study of the BrainGate Neural Interface System Read the paper May 2023 Months-long high-performance fixed LSTM decoder for cursor control in human intracortical brain-computer interfaces Read the paper Aug 2023 A High-Performance Speech Neuroprosthesis Read the paper Jan 2024 Co-occurring ripple oscillations facilitate neuronal interactions between cortical locations in humans. Read the paper Jan 2024 Brain Control of Bimanual Movement Enabled by Recurrent Neural Networks Read the paper Feb 2024 Low frequency independent components: Internal neuromarkers linking cortical LFPs to behavior. Read the paper Apr 2024 An accurate and rapidly calibrating speech neuroprosthesis. Read the paper Apr 2024 BRAND: a platform for closed-loop experiments with deep network models. Read the paper Apr 2024 A flexible intracortical brain-computer interface for typing using finger movements. Read the paper 2004 BrainGate clinical trial starts (NCT00912041) at participants’ homes Read the paper Jul 2006 iBCI control of computer cursor, TV, prosthetic hand, simple robotic arm; participants with SCI Read the paper Dec 2008 Cursor control; participants with brainstem stroke, ALS Read the paper Mar 2011 1000+ days of neural cursor control Read the paper May 2012 Multi-dimensional robotic and prosthetic arm control, coffee drinking Read the paper Jun 2015 Point-and-click typing at 1,994 days Read the paper Oct 2015 Improved cursor control and speed with ReFIT decoder Read the paper Nov 2015 QWERTY and radial keyboard use, up to 24 correct characters per minute Read the paper Feb 2017 Typing at 39 correct characters per minute (3.7 bits per second) Read the paper Mar 2017 iBCI + FES restoration of arm and hand movement Read the paper Jan 2018 Decoder calibration and cursor control in < 4 minutes Read the paper Sep 2018 Deep learning via LFADS reveals neural dynamics from single trials Read the paper Dec 2019 Phoneme decoding from hand motor cortex Read the paper Aug 2020 Power saving for wireless iBCIs Read the paper Mar 2021 Full bandwidth, external wireless home use Read the paper May 2021 Brain-to-text decoding of handwriting Read the paper Jun 2022 Learned Motor Patterns Are Replayed in Human Motor Cortex during Sleep Read the paper Jan 2023 Interim Safety Profile from the Feasibility Study of the BrainGate Neural Interface System Read the paper Aug 2023 A High-Performance Speech Neuroprosthesis Read the paper Co-occurring ripple oscillations facilitate neuronal interactions between cortical locations in humans. Read the paper Feb 2005 A point process framework for relating neural spiking activity to spiking history, neural ensemble and extrinsic covariate effects Read the paper Mar 2005 Reconstruction of hand movement trajectories from a dynamic ensemble of spiking motor cortical neurons Read the paper Mar 2007 Nonparametric modeling of neural point processes via stochastic gradient boosting regression Read the paper Sep 2008 Turning thought into action Read the paper Dec 2008 Neural activity in primary motor cortex correlates with intended movement kinematics in humans with tertraplegia Read the paper Jul 2009 The science of neural interface systems Read the paper Dec 2009 Predicting single neuron spikes Read the paper Jan 2010 Stochastic point process framework for the modeling, analysis and decoding of neuronal ensembles Read the paper Apr 2010 Intracortical microelectrode signals reveal heterogeneous neuronal firing patterns during interictal epileptiform discharges Read the paper Mar 2011 Single-neuron dynamics in human focal epilepsy Read the paper Apr 2013 Somatosensory responses in a human motor cortex Read the paper Jun 2014 Field potentials provide comparable offline decoding performance to unsorted spikes Read the paper Jul 2014 Neuronal ensemble synchrony during human focal seizures Read the paper Aug 2014 Early detection of human focal seizures based on cortical multiunit activity Read the paper Apr 2015 The emergence of single neurons in clinical neurology Read the paper Jun 2015 Neural population dynamics in human motor cortex during movements in people with ALS Read the paper Nov 2015 Microdynamics of focal seizure propagation Read the paper Aug 2016 Predicting seizures with intracortical LFPs Read the paper Sep 2018 Deep learning via LFADS reveals neural dynamics from single trials Read the paper Nov 2018 Watching, imagining, or attempting a movement produces a unique pattern of neural activity Read the paper Apr 2019 Volitional LFP control by poeple with tetraplegia Read the paper Jul 2019 Intracortical neural activity predicts onset of focal seizures Read the paper Dec 2019 Phoneme decoding from hand motor cortex Read the paper Jan 2020 Neural representation of observed, imagined, and attempted force production Read the paper Apr 2020 The ‘hand knob’ area of premotor cortex is tuned to the entire body Read the paper May 2020 Researchers demonstrate replay of learned sequences during rest in human motor cortex Read the paper Jan 2021 The role of middle frontal gyrus in planning movements in response to auditory stimuli Read the paper Jan 2021 Decoding force information across different grasp types Read the paper Jun 2022 Learned Motor Patterns Are Replayed in Human Motor Cortex during Sleep Read the paper Jan 2024 Co-occurring ripple oscillations facilitate neuronal interactions between cortical locations in humans. Read the paper Jan 1995 Intracortical recording of brain activity for control of limb prostheses Read the paper Jan 1997 Cortical control of a robot using a time-delay neural network Read the paper Mar 2002 Instant neural control of a movement signal Read the paper Mar 2003 Robustness of neuroprosthetic decoding algorithms Read the paper Jun 2006 An international discussion on the state of the brain-computer interface field Read the paper Jul 2006 iBCI control of computer cursor, TV, prosthetic hand, simple robotic arm; participants with SCI Read the paper Oct 2006 Prosthesis development for the restoration of limb function Read the paper Oct 2006 Sensors for brain-computer interfaces Read the paper Jan 2007 Neuromotor prosthesis development Read the paper Mar 2007 Assistive technology and robotic control using motor cortex ensemble-based neural interface systems in humans with tetraplegia Read the paper Apr 2007 Intuitive prosthetic limb control Read the paper May 2007 Multi-state decoding of point-and-click control signals from motor cortical activity in a human with tetraplegia Read the paper Oct 2007 Hybrid RF/IR Telemetry for brain implantable neuroengineering applications Read the paper Sep 2008 Turning thought into action Read the paper Nov 2008 Future applications of neural interface systems Read the paper Dec 2008 Cursor control; participants with brainstem stroke, ALS Read the paper Jun 2009 Wireless implantable microelectronic device for transmitting cortical signals transcutaneously Read the paper Jul 2009 The science of neural interface systems Read the paper Feb 2010 Progress in wireless implantable microelectronic neuroengineering devices Read the paper Apr 2010 Decoding 3-D reach and grasp kinematics from high-frequency LFPs in primate primary motor cortex Read the paper Nov 2010 Efficient decoding with steady-state Kalman filter Read the paper Jan 2011 Decoding point-and-click control signals from motor cortical activity in a human with tetraplegia Read the paper Mar 2011 1000+ days of neural cursor control Read the paper May 2012 Multi-dimensional robotic and prosthetic arm control, coffee drinking Read the paper Jul 2012 Prediction of imagined single-joint movements in a person with high-level tetraplegia Read the paper Feb 2013 Evaluation of implantable wireless neural interface in nonhuman primates Read the paper Apr 2013 Role of intra-day signal instabilities on decoding performance Read the paper Apr 2013 A 100-channel fully implantable wireless broadband neural recording system Read the paper Jul 2013 Advances in iBCI sensors and decoding Read the paper Jul 2013 Improved iBCI control with closed-loop calibration Read the paper Sep 2014 Modulation depth estimation and variable selection in state-space models for neural interfaces Read the paper Oct 2014 Non-causally filtering intracortical neural signals improves BCI decoding Read the paper Dec 2014 Wireless use in nonhuman primates Read the paper Jun 2015 Point-and-click typing at 1,994 days Read the paper Oct 2015 Improved cursor control and speed with ReFIT decoder Read the paper Nov 2015 QWERTY and radial keyboard use, up to 24 correct characters per minute Read the paper Nov 2016 Feedback control policies employed during active iBCI control Read the paper Jan 2017 Multiscale semi-Markov dynamics for intracortical brain-computer interfaces Read the paper Feb 2017 Typing at 39 correct characters per minute (3.7 bits per second) Read the paper Mar 2017 Review on advances in intracortical BCI technology Read the paper Mar 2017 Recalibration of click decoder using data acquired during practical BCI use Read the paper Mar 2017 iBCI + FES restoration of arm and hand movement Read the paper Dec 2017 Comparing methods for intention estimation for decoder calibration in iBCIs Read the paper Jan 2018 Decoder calibration and cursor control in < 4 minutes Read the paper Jan 2018 Methods for reducing artifacts in iBCI recordings caused by FES stimulation Read the paper Feb 2018 How iBCI movements currently differ from able-bodied movements Read the paper Jul 2018 LFP-based BCI for everyday communication Read the paper Nov 2018 A new neural decoder based on gaussian process regression is more resistant to nonstationarities Read the paper Nov 2018 Control of tablet computer with iBCI Read the paper Mar 2019 Comparison of LSTM vs Kalman decoders Read the paper Jun 2006 An international discussion on the state of the brain-computer interface field Read the paper Jul 2006 iBCI control of computer cursor, TV, prosthetic hand, simple robotic arm; participants with SCI Read the paper May 2007 Multi-state decoding of point-and-click control signals from motor cortical activity in a human with tetraplegia Read the paper Dec 2008 Cursor control; participants with brainstem stroke, ALS Read the paper Jan 2011 Decoding point-and-click control signals from motor cortical activity in a human with tetraplegia Read the paper Mar 2011 1000+ days of neural cursor control Read the paper Jul 2013 Improved iBCI control with closed-loop calibration Read the paper Apr 2015 The emergence of single neurons in clinical neurology Read the paper Jun 2015 Point-and-click typing at 1,994 days Read the paper Oct 2015 Improved cursor control and speed with ReFIT decoder Read the paper Nov 2015 QWERTY and radial keyboard use, up to 24 correct characters per minute Read the paper Feb 2017 Typing at 39 correct characters per minute (3.7 bits per second) Read the paper Mar 2017 Recalibration of click decoder using data acquired during practical BCI use Read the paper Jan 2018 Decoder calibration and cursor control in < 4 minutes Read the paper Jul 2018 LFP-based BCI for everyday communication Read the paper Nov 2018 Control of tablet computer with iBCI Read the paper Dec 2019 Phoneme decoding from hand motor cortex Read the paper Feb 2020 Speech-related dorsal motor cortex activity does not interfere with iBCI cursor control Read the paper Nov 2020 Decoding speech from the ‘hand knob’ area of precentral gyrus Read the paper Mar 2021 Full bandwidth, external wireless home use Read the paper May 2021 Brain-to-text decoding of handwriting Read the paper Aug 2023 A High-Performance Speech Neuroprosthesis Read the paper Mar 2005 Reconstruction of hand movement trajectories from a dynamic ensemble of spiking motor cortical neurons Read the paper Jun 2006 An international discussion on the state of the brain-computer interface field Read the paper Oct 2006 Prosthesis development for the restoration of limb function Read the paper Jan 2007 Neuromotor prosthesis development Read the paper Mar 2007 Assistive technology and robotic control using motor cortex ensemble-based neural interface systems in humans with tetraplegia Read the paper Apr 2007 Intuitive prosthetic limb control Read the paper Sep 2008 Turning thought into action Read the paper Apr 2010 Decoding 3-D reach and grasp kinematics from high-frequency LFPs in primate primary motor cortex Read the paper May 2012 Multi-dimensional robotic and prosthetic arm control, coffee drinking Read the paper Jul 2012 Prediction of imagined single-joint movements in a person with high-level tetraplegia Read the paper Apr 2015 The emergence of single neurons in clinical neurology Read the paper Mar 2017 iBCI + FES restoration of arm and hand movement Read the paper Jan 2018 Methods for reducing artifacts in iBCI recordings caused by FES stimulation Read the paper Mar 2020 Improving the BCI user experience with robotic effectors Read the paper Jan 2021 Decoding force information across different grasp types Read the paper Jan 2023 Interim Safety Profile from the Feasibility Study of the BrainGate Neural Interface System Read the paper May 2023 Months-long high-performance fixed LSTM decoder for cursor control in human intracortical brain-computer interfaces Read the paper Apr 2024 A flexible intracortical brain-computer interface for typing using finger movements. Read the paper Oct 2014 Speech-specific tuning of neurons in human superior temporal gyrus Read the paper Dec 2019 Phoneme decoding from hand motor cortex Read the paper Feb 2020 Speech-related dorsal motor cortex activity does not interfere with iBCI cursor control Read the paper Nov 2020 Decoding speech from the ‘hand knob’ area of precentral gyrus Read the paper Jan 2023 Interim Safety Profile from the Feasibility Study of the BrainGate Neural Interface System Read the paper Aug 2023 A High-Performance Speech Neuroprosthesis Read the paper Apr 2024 An accurate and rapidly calibrating speech neuroprosthesis. Read the paper Apr 2010 Intracortical microelectrode signals reveal heterogeneous neuronal firing patterns during interictal epileptiform discharges Read the paper Mar 2011 Single-neuron dynamics in human focal epilepsy Read the paper Jul 2014 Neuronal ensemble synchrony during human focal seizures Read the paper Aug 2014 Early detection of human focal seizures based on cortical multiunit activity Read the paper Apr 2015 The emergence of single neurons in clinical neurology Read the paper Nov 2015 Microdynamics of focal seizure propagation Read the paper Aug 2016 Predicting seizures with intracortical LFPs Read the paper Jul 2019 Intracortical neural activity predicts onset of focal seizures Read the paper Mar 2020 Intracortical microelectrode array signals allow early detection of human epileptic seizures Read the paper Jan 2023 Interim Safety Profile from the Feasibility Study of the BrainGate Neural Interface System Read the paper