For people with locked-in syndrome – the inability to move and to speak despite being fully awake and alert (for example, due to brainstem injury or ALS), restoration of easy communication is a priority. Our research team is developing technologies that would re-enable the ability to control a cursor on a computer screen or to type on a virtual keyboard, simply by thinking about the movement of one’s own hand (for example, as if controlling a computer mouse).
Pandarinath C, Nuyujukian P, Blabe CH, Sorice BL, Saab J, Willett FR, Hochberg LR, Shenoy KV, Henderson JM.
Jarosiewicz B, Sarma AA, Bacher D, Masse NY, Simeral JD, Sorice B, Oakley EM, Blabe C, Pandarinath C, Gilja V, Cash SS, Eskandar EN, Friehs G, Henderson JM, Shenoy KV, Donoghue JP, Hochberg LR
Sci Transl Med. 2015 Nov 11;7(313):313ra179. doi: 10.1126/scitranslmed.aac7328.
Gilja V*, Pandarinath C*, Blabe CH, Nuyujukian P, Simeral JD, Sarma AA, Sorice BL, Perge JA, Jarosiewicz B, Hochberg LR, Shenoy KV, Henderson JM.
Nat Med. 2015 Oct;21(10):1142-5. doi: 10.1038/nm.3953. Epub 2015 Sep 28.