For people with locked-in syndrome – the inability to move and to speak despite being fully awake and alert (for example, due to brainstem injury or ALS) – restoration of easy communication is a priority. Our research team is developing technologies that would re-enable the ability to control a cursor on a computer screen or to type on a virtual keyboard, simply by thinking about the movement of one’s own hand (for example, as if controlling a computer mouse).
Willett FR, Avansino DT, Hochberg LR, Henderson JM, Shenoy KV.
High-performance brain-to-text communication via handwriting
Nature. 2021 May 12; 593: 249–54. doi: 10.1038/s41586-021-03506-2. Prior version as submitted to bioRxiv.
Nuyujukian P, Albites Sanabria J, Saab J, Pandarinath C, Jarosiewicz B, Blabe CH, Franco B, Mernoff ST, Eskandar EN, Simeral JD, Hochberg LR, Shenoy KV, Henderson JM.
Cortical control of a tablet computer by people with paralysis.
PLoS ONE. 2018 Nov 21; 13(11).
Pandarinath C, Nuyujukian P, Blabe CH, Sorice BL, Saab J, Willett FR, Hochberg LR, Shenoy KV, Henderson JM.
High performance communication by people with paralysis using an intracortical brain-computer interface.